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titleWelcome to IVA space!
Welcome to the

The Interactive Variant Analysis (IVA) tool is an open-source project

. Here you will find plenty of information regarding what IVA project is and how to use it. You can visit it at

http://bioinfodev.hpc.cam.ac.uk/web-apps/iva-v0.6/src/

Main Features

  • Most important high-quality variant studies normalized and integrated in just one server database
  • Rich variant annotation performed
  • Population frequencies calculated
    • Interactive web-based data mining tool based on IVA

    implemented to facilitate the filtering, analysis and interpretation of whole genome variant data. This interactive tool allows the identification of genes affected by deleterious variants that segregate along family pedigrees, case-control or sporadic samples.

    IVA has been developed as part of the OpenCGA project, making it easy to work with clinical and variant information stored in a Catalog and Variant storage instance.


    Main Features

    • Allow to load VCF files and samples together with clinical data
    • High-performance and scalable VCF and gVCF indexing
    • VCF normalization and variant annotation
    • Clinical interpretation analysis of samples and families

    Contact

    • Ignacio Medina
    • Joaquin Dopazo

    IVA is developed and maintained at University of Cambridge and CIPF, it is freely available at https://github.com/opencb/iva

    Latest news:

    Blog Posts
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    Variant Browser

    You can efficiently browse annotated and indexed variant datasets...studies using a web-based application. 


    Clinical Interpretation

    You can select samples and families to perform an interpretation analysis... Disease panels are also available...

    Genome Browser

    A genome browser based on Genome Maps allows for a interactive and smooth variant visualisation...



    Rich Configuration

    You can highly customise your IVA installation thanks to the rich configuration implemented. ..You can easily customise the navigation bar, welcome page or the CSS.

    Who is Using

    HGVA

    BRIDGE

    CIBERER?

    GEL

    IVA is a novel application but it is alrady sued in several top-level projects such as HGVA, BRIDGE, ...

    Developers

    Source Code

    Web based on IVA project at  https://github.com/opencb/iva/tree/app/hgva

    Server based on OpenCGA at  https://github.com/opencb/opencga

    Contributing

    IVA is a collaborative project that aims to integrate as many reference human studies as possible, you can contact us for feature request. If you want to contribute to the code you are more than welcome to contribute to IVA and OpenCGA


    Contributors

    Ximo

    Ciberer

    University Cambrdige

    GEL

    ...Dr. Joaquin Dopazo (CIPF)

    Dr. Stefan Gräf (Clinical School, University of Cambridge)

    Ignacio Medina (HPCS, University of Cambridge)


    Recent space activity

    Recently Updated
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